This discussion covers some of the more common adrenal hormone excesses, focusing primarily on hyperadrenocorticism (Cushing’s syndrome) in dogs. We will analyze this common endocrine disorder in terms of pathophysiology, diagnostic options, and treatment – all of which can be frustrating to determine for a patient. Also to be discussed is the controversial phenomenon of sex hormone excess (so called atypical Cushing’s syndrome) in dogs and hyperaldosteronism (Conn’s syndrome) in cats. Case discussions and personal preferences in terms of management will be reviewed.